/ 09 August 2023

Obesity reshapes the brain

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That’s the landmark finding from researchers at Cambridge University, who found that the brains of people who are overweight or obese are shaped differently from those of non-obese people. The study used an AI algorithm to analyse the MRI brain scans of 1,351 young people of different weights. It found that the hypothalamus – the key area of the brain that acts as the “appetite control centre” – was significantly larger in obese participants. That means hormones are “dysregulated”, mucking up the triggers that communicate fullness or hunger, making it harder for obese people to stick to a diet. Researchers say they aren’t sure whether the hypothalamus is inflamed by obesity or whether people with a larger hypothalamus are predisposed to carry more weight. So that’s a delight…

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